Mean Lung Dose: a Practical Index for Evaluation of Radiation Pneumonitis
نویسندگان
چکیده
منابع مشابه
Curcumin Mitigates Radiation-induced Lung Pneumonitis and Fibrosis in Rats
Radiation-induced lung injury is one of the most prominent factors that interfere with chest cancer radiotherapy, and poses a great threat to patients exposed to total body irradiation. Upregulation of pro-oxidant enzymes is one of the main mechanisms through which the late effects of ionizing radiation on lung injury can be exerted. Interleukin (IL)-4 and IL-13 are two important cytokines that...
متن کاملPolymorphisms in BMP2/BMP4, with estimates of mean lung dose, predict radiation pneumonitis among patients receiving definitive radiotherapy for non-small cell lung cancer
Single nucleotide polymorphisms (SNPs) in TGFβ1 can predict the risk of radiation pneumonitis (RP) in patients with non-small cell lung cancer (NSCLC) after definitive radiotherapy. Here we investigated whether SNPs in TGFβ superfamily members BMP2 and BMP4 are associated with RP in such patients. In total, we retrospectively analyzed 663 patients given ≥ 60 Gy for NSCLC. We randomly assigned 3...
متن کاملEvaluation of the Influence of Exposure Index on Image Quality and Radiation Dose
Introduction: The introduction of digital radiography has led to a significant problem in terms of dose creep. To address this problem, manufacturers have established a set of exposure indicators (EI) as a feedback mechanism to safeguard against overexposure. The EI is the measure of incident exposure to the detector that is directly proportional to the signal-to-noise...
متن کاملExclusion of emphysematous lung from dose-volume estimates of risk improves prediction of radiation pneumonitis
BACKGROUND The risk factors for radiation pneumonitis (RP) in patients with chronic obstructive pulmonary disease (COPD) are unclear. Mean lung dose (MLD) and percentage of irradiated lung volume are common predictors of RP, but the most accurate dosimetric parameter has not been established. We hypothesized that the total lung volume irradiated without emphysema would influence the onset of RP...
متن کاملRadiation pneumonitis and pulmonary function with lung dose–volume constraints in breast cancer irradiation
PURPOSE We studied symptomatic radiation pneumonitis (RP) and changes in pulmonary function tests (PFTs) after loco-regional radiotherapy (LRRT) with V20 lung constraints in breast cancer (BC). PATIENTS AND METHODS Sixty-four women underwent PFTs before and 5 months after 3D planned LRRT for BC. The incidentally irradiated ipsilateral lung V20 was minimised to <30%. Patients were monitored fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Haigan
سال: 2007
ISSN: 1348-9992,0386-9628
DOI: 10.2482/haigan.47.695